Veeam Backup – The file is locked or in use — File open failed: File not open –tr:Failed to start file downloading. VMFS path

22/08/2022 2:13:58 AM :: Processing XXXXX Error: Failed to prepare VM for processing: DiskLib error: [13].The file is locked or in use — File open failed: File not open
–tr:Failed to start file downloading. VMFS path: [[XXXXX] XXXXXXXX.vmx].
–tr:NFC storage connection is unavailable. Storage: [stg:datastore-24292,nfchost:host-10905,conn:XXXX.ad.idplawyers.com.au]. Storage display name: [XXXXXX].
Failed to create NFC download stream. NFC path: [nfc://conn:XXXXXXXXXX,nfchost:host-109

Solution 

You need to restart the ESX Host 

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